Heterogeneity of human circulating anticoagulants against antihemophilic factor (factor VIII)
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چکیده
منابع مشابه
Heterogeneity of human circulating anticoagulants against antihemophilic factor (factor VIII).
The heterogeneity of human circulating anticoagulants against antihemophilic factor (AHF, factor VIII) observed in seven patients, both with and without classic hemophilia, was investigated by neutralization of their activity with antiserums directed to whole IgG and to lambda and kappa light chains. All seven anticoagulants were immunoglobulins. Six appeared to contain both kinds of light chai...
متن کاملHeterogeneity of Human Circulating Anticoagulants Against Antihemophilic Factor
The heterogeneity of human circulating serum. In one circulating anticoagulant, anticoagulants against antihemophilic light chain specificity could not be demonfactor (AHF, factor VIII) observed in seven strated with small amounts of antiserum, patients, both with and without classic and with larger amounts, only lambda hemophilia, was investigated by neutrallight chain specificity was revealed...
متن کاملHeterogeneity of Human Circulating Anticoagulants Against Antihemophilic
The heterogeneity of human circulating serum. In one circulating anticoagulant, anticoagulants against antihemophilic light chain specificity could not be demonfactor (AHF, factor VIII) observed in seven strated with small amounts of antiserum, patients, both with and without classic and with larger amounts, only lambda hemophilia, was investigated by neutrallight chain specificity was revealed...
متن کاملTechniques for demonstration of the specificity of circulating anticoagulants against antihemophilic factor (factor VIII), with studies of two cases possibly related to diphenylhydantoin therapy.
Circulating anticoagulants against antihemophilic factor (AHF, factor VIII) sometimes seem to inactivate other clotting factors as well. Measurements of the concentration of clotting factors in highly diluted plasma, or after neutralization of the anticoagulant with purified AHF, have demonstrated the specific nature of the anticoagulant in a patient under treatment with diphenylhydantoin. A se...
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ژورنال
عنوان ژورنال: Blood
سال: 1975
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v46.3.409.bloodjournal463409